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Brief
LiftDNA was acquired by OpenX.

LiftDNA

Programmatic Advertising

LiftDNA helped digital publishers maximize ad revenue by connecting their inventory to multiple demand sources through real-time bidding technology, increasing competition and driving higher CPMs.

Last updated Jun 17, 2026 by ATDb automated enrichment

Founded
2008
HQ
San Francisco, California, United States
Parent
Connections
2

At a glance

Employees
11-50
1integrations1corporate family

About

Early-stage SSP competing in the emerging programmatic marketplace for publisher monetization before being acquired by OpenX in 2012

LiftDNA was a supply-side platform (SSP) founded to help digital publishers optimize their advertising inventory through programmatic selling and real-time bidding (RTB) technology. The platform enabled publishers to connect with multiple demand sources simultaneously, increasing competition for their ad inventory and maximizing yield. LiftDNA positioned itself as a publisher-focused solution in the rapidly growing programmatic advertising ecosystem of the early 2010s. The company operated during a pivotal period in AdTech when SSPs were emerging as critical infrastructure for publishers seeking to move beyond direct sales and traditional ad networks. LiftDNA competed with other early SSPs such as PubMatic, Rubicon Project, and The Rubicon Project, all vying to become the preferred monetization layer for web publishers. Its technology focused on header bidding precursors, auction mechanics, and demand aggregation to drive higher CPMs for its publisher clients. On February 27, 2012, OpenX acquired LiftDNA, integrating its technology and publisher relationships into OpenX's broader ad serving and SSP platform. The acquisition allowed OpenX to strengthen its supply-side capabilities and expand its publisher base. Following the acquisition, LiftDNA ceased to operate as an independent brand and was absorbed into OpenX, which went on to become one of the leading independent SSPs in the programmatic advertising industry.

Business model

Marketplace

Target market

Mid-Market

What they offer

  • Supply-Side Platform

    Core SSP technology enabling publishers to sell ad inventory programmatically across multiple demand sources

  • Real-Time Bidding Integration

    RTB infrastructure connecting publisher inventory to DSPs and ad exchanges for auction-based selling

  • Yield Optimization

    Tools to help publishers maximize revenue by managing floor prices and demand partner prioritization

Key features

Real-time bidding (RTB) supportMulti-demand source aggregationPublisher yield optimizationAd inventory managementReporting and analytics dashboard

Use cases

Publisher ad inventory monetizationProgrammatic direct and open auction sellingRevenue optimization for web publishersDemand partner management

Customer segments

Digital publishersOnline media companiesContent websites seeking programmatic monetization

Tech & specs

Technology stack

Real-time bidding infrastructureAd serving technologyAuction mechanicsData analytics

Deployment

Cloud

API

Yes

Corporate history
  • 2008Founded
Connection details

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